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Presentation of INSERM UMR 1125 Physiopathology, targets and therapies of rheumatoid arthritis

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INSERM UMR 1125 is located in University of Paris 13,  in Bobigny. 

It belongs to the Multi-Organizations Thematic Institute (ITMO) “Circulation, métabolism, nutrition”.
For your information, the Alliance for Life and Health’s Sciences (Aviesan) groups ITMOs and other organisms such as 
INSERM, CNRS, INRA, CEA and universities together.

Research in INSERM UMR 1125 Physiopathology, targets and therapies of rheumatoid arthritis

Studies conducted  in the laboratory are at the cross point of several scientific and medical areas. They concern acute and chronic inflammation, immunopathology of diseases and biotherapies of inflammation, applied to the field of joint diseases.


Our laboratory is specifically focused in rheumatoid arthritis, investigated in a translational way, with a close relationship between patients and research. However, research applications also involve most of the chronic inflammatory diseases.


Among the characteristics of our lab, the use of experimental models of chronic inflammation (and chronic or relapsing arthritis) can parrallel studies in humans regarding the mechanisms involved.
This research strategy is reflected by the skills of the people of thelaboratory’s team, where scientists and doctors work together. The rheumatology department of the Avicenne hospital (Hospital Group Avicenne - Jean Verdier - René Muret, Assistance Publique-Hôpitaux de Paris) is in close relationship with our UMR, both entities working in a common University Hospital project.

Main achievements of the laboratory in recent years

INSERM UMR1125 is founded on a structure of university Paris 13 (EA 4222), created in 1996.
Since its birth in 1996, twenty PhD theses were defended and about a hundred of articles have been published in international peer reviewed journals on the topics of the laboratory. Among the advances, we can cite some examples:

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Research funding

Most research funding of UMR 1125 comes from public organizations, as INSERM and Paris 13 University.

Others research funding are obtained from different organizations through a competitive process. They come from research funding organizations such as INSERM, Agence Nationale pour la Recherche (national consortium CYTOVAC established by our lab), Fondation pour la Recherche Medicale, General Directorate for Armament and associations such as Arthritis-Fondation Courtin and French Society for Rheumatology (“Société Française de Rhumatologie“). Pharmaceutical industries helps our research under two forms : an industry-university partnerships can be done to develop together projects or they help our researches with grants.

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Campus of Bobigny

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