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Publications of INSERM UMR 1125


  • Syngeneic fibroblasts engineered to secrete interleukin-4 as vectors for antiinflammatory gene therapy in collagen-induced arthritis. Bessis N, Cottard V, Saidenberg-Kermanac’h N, Lemeiter D, Fournier C, Boissier MC.  J Gene Med, 2002, 4 :300-7
  • Osteoprotegerin and inflammation. Saidenberg-Kermanac’h N, Bessis N, Cohen-Solal M, de Vernejoul M, Boissier MC.  Eur Cytokine Netw, 2002, 13 :144-53
  • Gene therapy for rheumatoid arthritis. Bessis N, Doucet C, Cottard V, Douar AM, Firat H, Jorgensen C, Mezzina M, Boissier MC  J Gene Med, 2002 ;4 :581-91


  • Detection of nucleosome particles in the sera of patients with SLE using monoclonal antibody 4H7. Williams RC, Malone CC, Meyers C, Decker P, Muller S.  J Rheumatol, 2001, 28:81-94.ardiac manifestations of rheumatoid arthritis : a case control transoesophageal echocardiography study in 30 patients. Guedes C, Bianchi-Fior P, Cormier B, Barthelemy B, Rat AC, Boissier MC. C Arthritis Rheum , 2001, 45:129-35.
  • Collagen II-pulsed antigen-presenting cells engineered to secrete IL-4 down regulate collagen-induced arthritis. Guéry L, Chiocchia G, Batteux F, Boissier MC C, Fournier C.  Gene Ther, 2001, 8 : 1855,62


  • Adeno-associated virus mediated delivery of IL-4 prevents collagen-induced arthritis. Cottard V, Mulleman Bouillé P, Mezzina M, Boissier MC, Bessis N.  Gene Ther, 2000; 7: 1930-9Expression of fas ligand improves the therapeutic effect if IL-4 in collagen-induced arthritis Guéry L, Batteux F, Bessis N, Bréban M, Boissier MC, Fournier C, Chiocchia G. . Eur J Immunol, 2000;30:308-15
  • The type II decoy receptor of IL-1 inhibits murine collagen-induced arthritis. Bessis N, Guéry L, Mantovani A, Vecchi A, Sims J, Fradelizi D, Boissier MC.  Eur J Immunol,2000;30:867-75Inhibition of caspase-3-mediated poly(ADP-ribose) polymerase apoptotic cleavage by human PARP autoantibodies and effect on cells undergoing apoptosis. Decker P, Isenberg DA, Muller S.  J Biol Chem, 2000, 275:9043-6.
  • Molecular and structural properties of three autoimmune IgG monoclonal antibodies to histone H2B. Monestier M, Decker P, Briand JP, Gabriel JL, Muller S.  J Biol Chem, 2000, 275:13558-63.
  • Identification of a minimal T cell epitope recognised by anti-nucleosome Th cells in the C-terminal region of histone H4. Decker P, Le Moal A, Briand JP, Muller S.  J Immunol, 2000, 165:654-62.

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